THE IMPACT OF MATERNAL OBESITY ON PREGNANCY – A REVIEW ARTICLE

  • Maja Pejkovska Ilieva University Clinic for Gynecology and Obstretics, Faculty of Medicine, "Ss. Cyril and Methodius" University in Skopje, North Macedonia

Abstract

Maternal obesity has been estimated as a global epidemic, affecting 40% of pregnant women in developed nations. The weight of females that are pregnant has become one of the most concerning points in the modern obstetrics. For this matter after consulting the most accurate literature from academic books in the field and from internet sources from the year 2020 until the year 2025 available on PubMed, Scopus, Data of Science, Google Scholar, ResearchGate, Academia and others we have created a review article that takes in consideration the impact of maternal obesity on the pregnancy itself. Women may have been obese before becoming pregnant or they may have rapidly gained weight during pregnancy and the types of maternal obesity have their challenges for the pregnancy outcome. The maternal obesity must be carefully treated since it is directly responsible for the impact on gestational diabetes mellitus (GDM), hypertensive disorders, and various perinatal complications. By analyzing the types of maternal obesity and complications that occur during pregnancy we take care not only for the current health of the pregnant mothers and their babies but also of their future to take preventive measures, lifestyle changes and thus to improve their health and the health of their babies.


Key words: maternal obesity, pregnancy outcome, diabetes mellitus, hypertension, perinatal complications.

References

1. World Health Organization. Obesity. https://www.who.int/health-topics/obesity#tab=tab_1
(accessed 1 Oct 2021)
2. Safaei M, Sundararajan EA, Driss M, Boulila W, Shapii A. A systematic literature review on obesity understanding the causes and consequences of obesity and reviewing machine learning approaches used to predict obesity. Comput Biol Med. 2021;136:104754. doi:10.1016/j.compbiomed.2021.104754
3. Nelson SM, Matthews P, Poston L. Maternal metabolism and obesity modifiable determinants of pregnancy outcome. Hum Reprod Update. 2010;16(3):255-275. doi:10.1093/humupd/dmp050
4. Kent L, McGirr M, Eastwood KA. Global trends in maternal overweight and obesity a systematic review and meta-analysis. Int J Popul Data Sci. 2024;9(2):6. doi:10.23889/ijpds.v9i2.2401
5. Mayo Clinic. Pregnancy and obesity. https://www.mayoclinic.org/healthy-lifestyle/pregnancy-week-by-week/in-depth/pregnancy-and-obesity/art-20044409
(accessed 1 Oct 2021)
6. Abdi F, Alizadeh S, Roozbeh N et al. Prepregnancy overweight and obesity and risk of adverse pregnancy outcomes. Sci Rep. 2025;15:16846. doi:10.1038/s41598-025-02113-9
7. Reed J, Case S, Rijhsinghani A. Maternal obesity perinatal implications. SAGE Open Med. 2023;11:20503121231176128. doi:10.1177/20503121231176128
8. Abrams BF, Leonard SA, Kan P, Lyell DJ, Carmichael SL. Interpregnancy weight change and associations with severe maternal morbidity and neonatal outcomes. Am J Obstet Gynecol MFM. 2022;4:100596. doi:10.1016/j.ajogmf.2022.100596
9. Heslehurst N, Vinogradov R, Nguyen GT et al. SHAPES protocol for adiposity in pregnancy and outcomes. BMJ Open. 2023;13(9):e073545. doi:10.1136/bmjopen-2023-073545
10. World Bank. High income data. https://data.worldbank.org/country/XD
(accessed 1 Oct 2021)
11. Johansson K et al. Safety of low weight gain or weight loss in pregnancies with class 1 2 and 3 obesity a population-based cohort study. Lancet. 2024;403(10435):1472-1481
12. Bashir M, Fagier Y, Ahmed B, Konje JC. Overview of diabetes mellitus in pregnant women with obesity. Best Pract Res Clin Obstet Gynaecol. 2024;93:102469. doi:10.1016/j.bpobgyn.2024.102469
13. Garovic VD, Dechend R, Easterling T et al. Hypertension in pregnancy diagnosis blood pressure goals and pharmacotherapy. Hypertension. 2022;79(2):e21-e41
14. Poon LC, Magee LA, Verlohren S et al. Second and third trimester risk stratification and management of pre-eclampsia. Int J Gynecol Obstet. 2021;154:3-31
15. Wagata M, Kogure M, Nakaya N et al. Hypertensive disorders of pregnancy obesity and later-life hypertension. Hypertens Res. 2020;43:1277-1283. doi:10.1038/s41440-020-0463-8
16. Poniedzialek-Czajkowska E, Mierzynski R, Leszczynska-Gorzelak B. Preeclampsia and obesity the preventive role of exercise. Int J Environ Res Public Health. 2023;20:1267. doi:10.3390/ijerph20021267
17. Aedla NR, Mahmood T, Ahmed B, Konje JC. Challenges in timing and mode of delivery in morbidly obese women. Best Pract Res Clin Obstet Gynaecol. 2024;92:102425. doi:10.1016/j.bpobgyn.2023.102425
18. Horwood G, Erwin E, Guo Y et al. Risk associated with planned mode of delivery in women with obesity. Int J Obes. 2025;49:835-843. doi:10.1038/s41366-024-01709-x
19. Beam Legal Team. Maternal risk factors for shoulder dystocia. https://www.beamlegalteam.com/blog/maternal-risk-factors-for-shoulder-dystocia/
20. Kim J, Ayabe A. Obesity in pregnancy. In StatPearls. Treasure Island FL StatPearls Publishing; 2025. https://www.ncbi.nlm.nih.gov/books/NBK572113/
Published
2025-11-18
How to Cite
ILIEVA, Maja Pejkovska. THE IMPACT OF MATERNAL OBESITY ON PREGNANCY – A REVIEW ARTICLE. Journal of Morphological Sciences, [S.l.], v. 8, n. 2, p. 180-185, nov. 2025. ISSN 2545-4706. Available at: <https://www.jms.mk/jms/article/view/vol8no2-20>. Date accessed: 30 nov. 2025.
Section
Articles