PERFORATION OF SMALL INTESTINE IN PREMATURE NEONATE - POSTOPERATIVE MANAGEMENT CASE REPORT

  • Silvana Naunova Timovska University Clinic for Pediatric Diseases, Faculty of Medicine, University "St. Cyril and Methodius" University in Skopje, North Macedonia
  • Hristina Mandzukovska University Clinic for Pediatric Diseases, Faculty of Medicine, University "St. Cyril and Methodius" University in Skopje, North Macedonia
  • Iskra Martinovska PHI Special Hospital for Gynecology and Obstetrics “Mother Teresa” – Chair, Skopje, North Macedonia
  • Olgica Atanasova University Clinic for Pediatric Diseases, Faculty of Medicine, University "St. Cyril and Methodius" University in Skopje, North Macedonia
  • Eva Kraljeva University Clinic for Pediatric Diseases, Faculty of Medicine, University "St. Cyril and Methodius" University in Skopje, North Macedonia

Abstract

 ­Gastrointestinal perforation (GIP) in neonates is a severe, acute, life-threatening condition associated with multiple complications and a high mortality rate. It is most often associated with necrotizing enterocolitis, but it also often occurs spontaneously due to local intestinal ischemia. Early detection and timely surgical intervention, with appropriate respiratory support and individualized nutritional support, are crucial in the outcome and survival of extremely premature neonates. We present a case of postoperative management of an extremely premature infant from a twin pregnancy after surgical intervention due to intestinal perforation.


Keywords: premature neonate, spontaneous gastrointestinal perforation, necrotizing enterocolitis


 

References

1.Wei Feng,Hong Zhang,Huan Yan,Zheng-Bing Yang,Jin-Liang Zhao,Li-Bing Zhang. Gastrointesti-nal perforation in extremely low birth weight infants: A single center retrospective study in Chi-na.Pediatr Neonatol 2024 ;65(2):111-116.
2.Blakely, Martin L. MD ; Lally, Kevin P. MD ; McDonald, Scott BS; Brown, Rebeccah L. MD ; Barnhart, Douglas C. MD ; Ricketts, Richard R. MD et al.Postoperative Outcomes of Extremely Low Birth-Weight Infants With Necrotizing Enterocolitis or Isolated Intestinal Perforation:A Pro-spective Cohort Study by the NICHD Neonatal Research Network. Annals of Surgery 2005;241:984-994.
3.Lee JY, Namgoong JM, Kim SC, Kim DY. Usefulness of peritoneal drainage in extremely low birth weight infants with intestinal perforation: a single-center experience. Ann Surg Treat Res 2020;98:153–7.
4. Lianou L, Petropoulou C, Lipsou N, Bouza H. Difference in mortality and morbidity between extremely and very low birth weight neonates. Neonatal Netw 2022;41: 257–62.
5. Chawla D. Survival of extremely-low-birth-weight neonates in India. Indian J Pediatr 2023;90:217–8.
6. Kombo L, Smith J, Van Wyk L. Somatic growth of enteral-only fed extremely low birth weight infants in a resource-restricted setting. J Trop Pediatr 2021;67: fmaa119.
7. Zeigler AC, Ainsworth JE, Fairchild KD, Wynn JL, Sullivan BA. Sepsis and mortality prediction in very low birth weight infants: analysis of heRO and nSOFA. Am J Perinatol 2023;40:407–14.
8. Nan Ye,Yurong Yuan, Lei Xu,Riccardo E. Pfister&Chuanzhong Yang. Successful conservative treatment of intestinal perforation in VLBW and ELBW neonates: a single center case series and review of the literature. BMC Pediatrics volume 19, Article number: 255 (2019)
Published
2025-05-02
How to Cite
NAUNOVA TIMOVSKA, Silvana et al. PERFORATION OF SMALL INTESTINE IN PREMATURE NEONATE - POSTOPERATIVE MANAGEMENT CASE REPORT. Journal of Morphological Sciences, [S.l.], v. 8, n. 1, p. 189-192, may 2025. ISSN 2545-4706. Available at: <https://www.jms.mk/jms/article/view/vol8no1-25>. Date accessed: 01 oct. 2025.
Section
Case Report