TY - JOUR AU - Popovska, Mirjana AU - Polozhani, Nora AU - Spasova, Olga AU - Boskovska, Katerina PY - 2022 TI - SKIN MANIFESTATIONS IN CHILDREN WITH COVID 19 JF - Journal of Morphological Sciences; Vol 5 No 3 (2022): JMS KW - N2 - Children are a unique subgroup of patients in relation to the COVID-19 pandemic, often presenting asymptomatically, mildly or atypically. Initial reports did not include skin manifestations as a feature of COVID-19, however, there is a growing repertoire of reports showing a range of dermatologic skin manifestations in children. Six clinical manifestations have been described: urticaria, maculo-papular rash, morbilliform eruption, vesicular rash, lividor-reticular and multiform rash. Dermatological features occur before or simultaneously with other manifestations of COVID-19. Doctors play a key role in diagnosing patients with COVID-19 who may present for the first time unknowingly showing early signs of the disease. In this report are presented 4 cases of patients with Covid 19 infection, where the skin is the target organ of the virus. In all children, the skin manifestation is different, their markers of inflammation are different and the treatment is not the same. In patient number 1, we look at the benefit of I.VIG in viral infections and consider their use in COVID-19 infection. Skin changes should never be ignored. The rash can spread and lead to a severe form of the disease. Skin manifestations may be the primary (or only) manifestation of a sign. It is extremely important to recognize it in time and to treat it accordingly. Keywords : Children, Covid 19, Immunoglobulins, Skin changes. UR - http://www.jms.mk/jms/article/view/vol5no3-9